Reactive intermediates
We use electrochemical control to generate reactive species at low steady-state concentration and couple their formation directly to productive bond-forming reactions.
Synthetic Electrochemistry at the University of Greenwich
Electrosynthesis from reactive intermediates to scalable processes
We develop electrochemical methods for reactions that are hazardous, difficult to control or challenging to scale. By combining organic synthesis, electroanalysis and reactor design, we connect electron transfer with selectivity and translate useful chemistry into reproducible batch and flow processes.
€7M+ securedAs principal investigator or co-investigator
30+ alumni and visiting researchersAn international network spanning academia, pharmaceutical research, process chemistry and scientific publishing
Cross-sector partnershipsCollaborations with universities, research organisations, pharmaceutical companies and instrument manufacturers
Research
Our research programme
Our research addresses three connected challenges: generating reactive intermediates under controlled conditions, understanding how electron transfer governs selectivity, and translating promising reactions into reproducible batch and flow processes.
Mechanism and selectivity
We combine voltammetry, controlled-potential experiments, spectroscopy, kinetics and computation to test how electron transfer, mass transport and reaction conditions determine selectivity.
Flow and scale-up
We translate useful transformations from discovery-scale experiments into controlled batch and flow processes, with attention to current density, electrode geometry, mixing, heat transfer and residence time.
Featured publication | Nature Communications
Divergent electrochemical fluorination of secondary amines
Starting from secondary amines, this one-pot electrochemical platform provides either thiocarbamoyl fluorides or N-trifluoromethyl amines by changing the reaction conditions. The method uses practical reagents, supports late-stage modification and is accompanied by mechanistic analysis.
Two fluorinated product classes from one electrochemical platform.
Recent work
Recent publications
Chemical Science, 2026
eCyclopropanation: a safe and scalable electrochemical route to cyclopropanes
The sequence generates diazo intermediates from hydrazones and consumes them directly in Rh(II)-catalysed cyclopropanation, with reaction development, mechanistic evidence and demonstrations in batch and continuous flow.
Organic Letters, 2026
Electrochemical Trideuteromethylation with AcOD-d₄: A Route to CD₃-Labeled Building Blocks
An electrochemical method installs CD₃ from AcOD-d₄ under batch and flow conditions. The study provides access to trideuteromethylated building blocks from an inexpensive deuterium source.
ACS Electrochemistry, 2026
eCyanation: A Dual Strategy for Electrochemical Cyanation of Amines Using Potassium Thiocyanate
This study uses bench-stable potassium thiocyanate in complementary electrochemical cyanation modes. Electrochemical control links reagent activation with selective C–CN bond formation.
Facilities and capabilities
From reaction discovery to process translation
Dedicated group facilities connect electrosynthesis, electroanalysis, flow processing, purification and analytical feedback in one working environment.
The equipment supports rapid feedback from mechanistic insight and reaction discovery through to batch and flow translation.
Our group
Meet the people behind the research
The group brings together researchers in organic synthesis, electroanalysis, reaction mechanism, reactor design and process translation.
Contact